The fire sparked about 2 a.m. Monday at a body shop in the 1700 block of Northwest 5th Street.
A police officer saw smoke in the area and called 911.
Firefighters found several cars inside the building on fire.
Crews believe the fire initially began in one vehicle and spread to the rest.
HazMat crews were called in as a precaution.
The estimated cost of the damage is approximately $120,000.