Oklahoma State improved to 6-1 on the year after pulling away from Iowa State 58-27.
The Cowboys avoided being upset in their second straight trip to Ames and were paced offensively by Desmond Roland.
In his first career start Roland rushed for a career high 219 yards and four touchdowns.
The Cowboys also became bowl eligible with the win but have their sights set much higher.
Dylan Buckingham has the story from Iowa.