With just over a minute left in the first half, Oklahoma was trailing lowly Iowa State 10-3 and were not playing with much enthusiasm or emotion.
That changed when Jalen Saunders returned a punt 91 yards for a touchdown, and it began a 45-0 OU run to end the game, fueled by big plays.
OU had four touchdowns of 56 yards or more, and coasted to a 48-10 win over the Cyclones.
Dylan Buckingham reports from Norman.