Young patients are at risk of harming themselves if they receive doses of antidepressants that are higher than recommended, a new study says.
There has been mixed evidence on the subject of antidepressant and suicidal behavior among youth in the past.
A government review found an association with self-harm, prompting a so-called “black box warning,” or warning on the drug’s label.
But other studies have found no link, and argue that the benefits of these drugs outweigh the risks.
This study, however, specifically examines the connection to dose levels. It looked at three popular drugs: Celexa, Zoloft and Prozac.
Researchers found a risk in self-harm associated with higher-than-recommended doses in patients under age 24.
They did not find the same effects in individuals over age 25, or those who took lower drug dosages.
Further study is needed.