When two schools like this get together there's no doubt about the hype surrounding the game.
I spoke with one OU staffer who's been around a couple decades he said, he thinks it's the biggest home game since 2000 Nebraska.
Which is ironically the last time oddsmakers felt the Sooners were underdogs on this field.
But there's no doubting the tradition between these two schools a combined 12 Heisman trophies, 12 AP national titles and 80 conference championships.
"This is definitely a game I came here for," Steven Parker, an OU safety from Tulsa, said. "Just being an instate guy. It's something that I've dreamed about my whole life, and I'm pretty sure everybody on the team's dreamed about the same reason to come to Oklahoma and be a Sooner.”
"I think they're kind of similar, the big games," Mark Andrews, OU sophomore tight end, said. "There's a lot of hype around those games. They're important for our season for sure. Last year's game against Tennessee was a big turning point for our season I think, and a big win for us. So I think we're just going into this game knowing that there's a lot on this game. There's going to be some of the similar factors between last year and this year.”
"I think it's exciting for college football fans that even aren't Oklahoma or Ohio State fans," Bob Stoops, OU head football coach, said. "Everybody likes to see these kinds of matchup's. They're exciting for everybody really."
There's only been two times in the Bob Stoops era OU has welcomed a top three opponent on this field.
Both of which became iconic wins: 2008 Texas Tech, and 2000 Nebraska.