SPD officials say officers responded to 810 S. Jardot on an assault with a deadly weapon call at 12:09 a.m. Saturday.
Upon arrival, police found an unresponsive male with multiple stab wounds.
SPD officers attempted to perform life-saving measures, but he was later pronounced deceased by medical personnel.
SPD officials say a person of interest has been identified, but the case is still under investigation.
Anyone with any information is asked to contact the SPD Tipline at 405-533-8477.